You've always known this could happen, and now it has. Your Chronic Lymphocytic Leukemia (CLL) has returned, or relapsed. That means that your leukemia cells are, once again, growing and crowding out the normal, healthy blood cells.
This time around though, your doctor has decided to try something different for your relapsed CLL — an alternative treatment approach. With ZYDELIG. ZYDELIG is a prescription medicine used to treat adults with Chronic Lymphocytic Leukemia (CLL) in combination with Rituxan® (rituximab) when the disease comes back after prior cancer treatment. It is used in patients who may otherwise be treated with Rituxan alone due to other health concerns.
It's not uncommon for a relapse diagnosis to take you by surprise. You may be feeling relatively well, with no or few symptoms, when you hear the news. Chances are your doctor confirmed your diagnosis through a combination of your medical history and one or more of the following tests:
Once your healthcare team has confirmed that you have relapsed CLL, they will have to determine how advanced it is, in order to develop the best treatment plan for you. Having been through this before, you may already be familiar with the different CLL stages and their symptoms.
Before beginning treatment for your relapsed CLL, it's important that you understand the goals of therapy. They include:
Having had CLL before, you're probably familiar with more conventional treatments. These include chemotherapy, where one or more medications are used to destroy fast-growing cells (including your cancer cells), and antibody therapy, which kills tumor cells directly or indirectly.
However, CLL treatment continues to evolve. With promising results from clinical trials, the outlook for patients with this disease is looking better and better. In fact, nowadays, there are new classes of treatments designed to block the growth and survival of B cells, some of which are cancerous. One such drug is a Phosphoinositide 3-Kinase (PI3K) delta inhibitor.
What is the most important information I should know about ZYDELIG?
ZYDELIG can cause serious side effects that can lead to death, including: