The tips included within this section come from organizations focused on supporting people with cancer.
This information is not meant to replace your doctor's advice. Be sure to talk to your doctor before you try any of these tips.
You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088. You can also call 1-800-GILEAD-5 (1-800-445-3235).
One common side effect of ZYDELIG® therapy is diarrhea, or frequent and watery bowel movements. Avoid using ZYDELIG with other drugs that cause diarrhea.
Diarrhea can happen anytime, even several months after you begin treatment. Be sure to tell your doctor or nurse right away if you notice any increase in the number of bowel movements you have in a day. If you have severe diarrhea while taking ZYDELIG, your doctor may completely stop your treatment, stop your treatment for a period of time, or change your dose of ZYDELIG. Reporting diarrhea is especially important because some cases can be managed to allow you to stay on therapy. In a series of clinical trials, some patients stopped therapy. Of the patients who experienced severe diarrhea, 67% were started at a lower dose. Of those patients, 58% who restarted treatment didn’t experience severe diarrhea again.2 Tell your doctor or nurse if you experience any increase in your number of daily bowel movements.
Make sure to tell your doctor or nurse if your diarrhea continues.Top of page
One of the most common side effects of ZYDELIG therapy is extreme tiredness, or fatigue. You may be experiencing fatigue if you can't seem to get enough sleep, have trouble focusing, or sometimes get confused.5 Be sure to tell your doctor or nurse as early as possible if you experience fatigue.
While taking ZYDELIG, you may experience nausea—the feeling of being sick to your stomach. Be sure to tell your doctor or nurse as early as possible if you experience nausea.
Tell your doctor or nurse right away if you have a fever while taking ZYDELIG. Fever may be a sign of infection. It is important to report fever or any signs of an infection to a doctor or nurse as early as possible.Top of page
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