Potential side effects with ZYDELIG®

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Tell your doctor or nurse as soon as you have any side effects or notice anything that seems out of the ordinary while taking ZYDELIG (idelalisib), even if it isn't a side effect listed on this website.

Side effects can occur at any time. The earlier your treatment team learns about potential side effects you're experiencing, the better chance they have to address the side effect and ensure ZYDELIG is still the most appropriate treatment for you. If addressed early, many side effects related to ZYDELIG can be managed.1,2

Serious side effects

Most common side effects

Tips for managing & reporting certain side effects

ZYDELIG is not indicated and is not recommended for first-line treatment of any patient, including patients with CLL, small lymphocytic lymphoma (SLL), follicular lymphoma (FL), and other indolent non-Hodgkin lymphomas.

ZYDELIG is not indicated and is not recommended in combination with bendamustine and Rituxan, or in combination with Rituxan for the treatment of patients with FL, SLL, and other indolent non-Hodgkin lymphomas.


  1. ZYDELIG® (idelalisib) [Prescribing Information]. Foster City, CA: Gilead Sciences, Inc.; rev February 2022.
  2. Targeted therapy side effects. American Cancer Society. Updated December 10, 2020. Accessed September 14, 2023. https://www.cancer.org/cancer/managing-cancer/treatment-types/targeted-therapy/side-effects.html